| Date | Level | Title | Vs | Home/Away |
|---|---|---|---|---|
| 07.23.2021 @ 7:00PM | Varsity | Mustang Football Horsepower Night | home | |
| 08.14.2021 @ 4:00PM | Varsity, J.V., Freshmen, Team | Bring Out the Bronco's | home | |
| 08.30.2021 @ 6:00PM | Freshmen | Mustang 9th v. Moore | Moore | away |
| 09.03.2021 @ 7:00PM | Varsity | Yukon | Yukon | home |
| 09.06.2021 @ 5:00PM | J.V., Freshmen | Mustang 9th/JV vs. Yukon | Yukon | away |
| 09.10.2021 @ 7:00 | Varsity | Stillwater | Stillwater | away |
| 09.13.2021 @ 5:00PM | Freshmen, J.V. | Mustang 9th/JV v. Stillwater | Stillwater | home |
| 09.17.2021 @ 7:00PM | Varsity | Norman | Norman | away |
| 09.20.2021 @ 5:00PM | Freshmen, J.V. | Mustang 9th/JV v. Norman | Norman | home |
| 09.20.2021 @ 6:30PM | Freshmen | Mustang 9th White v. Community Christian | Community Christian | away |
| 09.24.2021 @ 7:00PM | Varsity | Norman North | Norman North | away |
| 09.27.2021 @ 5:00PM | Freshmen, J.V. | Mustang 9th/JV v. Norman North | Norman North | |
| 10.01.2021 @ 7:00PM | Varsity | Southmoore | Southmoore | home |
| 10.04.2021 @ 5:00PM | Freshmen, J.V. | Mustang 9th/JV v. Southmoore | Southmoore | away |
| 10.08.2021 @ 7:00PM | Varsity | Union | Tulsa Union | away |
| 10.11.2021 @ 5:00PM | Freshmen, J.V. | Mustang 9th/JV v. Edmond Memorial | Edmond Memorial | home |
| 10.14.2021 @ 7:00PM | Varsity | Edmond North | Edmond North | home |
| 10.18.2021 @ 5:00PM | Freshmen, J.V. | Mustang 9th/JV v. Edmond North | Edmond North | away |
| 10.22.2021 @ 7:30PM | Varsity | Owasso | Owasso | away |
| 10.25.2021 @ 6:00PM | Freshmen | Mustang 9th White v. Community Christian | Community Christian | home |
| 10.25.2021 @ 6:00PM | Freshmen, J.V. | Mustang JV v. Norman North | Norman North | away |
| 10.29.2021 @ 7:00PM | Varsity | PCO | Putnam City | home |
| 11.01.2021 @ 5:00PM | Freshmen, J.V. | Mustang 9th/JV v. PCO | Putnam City | away |
| 11.05.2021 @ 7:00PM | Varsity | Moore | Moore | home |